KMID : 0358419960390122385
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Korean Journal of Obstetrics and Gynecology 1996 Volume.39 No. 12 p.2385 ~ p.2388
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The Best Period for Fetal Cell Isolation from Maternal Blood
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Áö°üÀÚ
±è¼®Âù/ÁöÀÏ¿î/¹®¿µ±Ô
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Abstract
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In the future, fetal cells in the maternal blood may be a source of material for routine screening for prenatal diagnosis in the first trimester for any woman who wishes to be tested. In order for this to become a reality, the timing of the
appearance
of fetal cells in the maternal circulation must be defined accurately.
So, our work have focused on "when during gestation can fetal cells best be recovered" and whether they are then present and available in sufficient numbers for analysis throughout the pregnancy. Samples were collected from 162 women pregnancy
between 7
and 25 weeks of gestation and we analyzed the nRBC ratin(%) within total isolated nucleated cells by differential counts(Diff-Quik stained). In this study, we have some conclusions ; The results of our study of fetal cell isolation was very
encouraging(sucessful rate : 91.35%). It is possible to isolation of nRBC in all pregnant women during 9~25 weeks of pregnancy, although the best period for fetal cell recover was 11~15 weeks of gestation.
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KEYWORD
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